S4-E15.5 - From the Vault: Advancing NASH Best Practices In NITs: “Stacking” NASH Biomarkers

Send us Fan MailThis week on Surfing NASH, co-hosts Jörn Schattenberg and Roger Green review the recently concluded Liver Forum. Joining discussion are Liver Forum Executive Director Veronica Miller and speakers Mazen Noureddin (Houston Research Institute), Michelle Long (Novo Nordisk) and Jeff McIntyre (Global Liver Institute).This conversation From the Vault begins with Quentin Anstee complimenting Stephen Harrison for his observation that when we analyze NASH biomarkers, we should consider the value of sustained response separate from early OR late response.From here, the group moves to the concept of “stacked” tests — confirmatory results from different NITs as a way to assess efficacy in an individual clinical trial subject. The conversation takes some twists and turns, but the core concept is unique, challenging and a significant step forward in the broader discussion of how to analyze biomarkers.If you enjoy the episode, have questions or interest around its contents and Fatty Liver disease, we kindly ask that you submit reviews wherever you download our discussions. Alternatively, you can write to us directly at [email protected] Safe and Surf On!