S5 Ep 15: Ergot Poisoning - Hallucinations and History episode artwork

EPISODE · Oct 1, 2025 · 1H 47M

S5 Ep 15: Ergot Poisoning - Hallucinations and History

from Science with The Blunt Letters · host The Blunt Letters

In the second installment of The Blunt Letters Poisoning Series, Elle and Micaela dive into the strange and terrifying history of ergot poisoning. From contaminated rye bread in the Middle Ages to its possible connection with the Salem Witch Trials, ergot has been haunting humanity for centuries. We explore the science of the fungus Claviceps purpurea, how it causes convulsions, hallucinations, and gangrene, and why it earned the nickname “St. Anthony’s Fire.” Plus, we discuss ergot’s surprising role in the discovery of LSD and its lasting impact on medicine, mysticism, and culture. Join us for a mix of history, toxicology, and true crime science in this deep dive into one of the world’s most notorious natural poisons.Featuring Original Song "Who Farted?" by Micaela SuperstarReferences:Ergot ErgotismLSDHow Rye Bread May Have Caused the Salem Witch TrialsErgotism TodayErgot: from witchcraft to biotechnology Were They Bitten? Or is it Ergot Poisoning?CIA sued over 1950s 'murder' of government scientist plied with LSDMK ultra wiki

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S5 Ep 15: Ergot Poisoning - Hallucinations and History

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