S9 Ep. 1: Gimme gimme shock treatment, part 1 (Inotropes and vasopressors)

Today's episode is the first in a series of three that focus on inotropic and vasopressor medications used within anaesthetic practice. During this episode, we discuss metaraminol, ephedrine, phenylephrine, noradrenaline and adrenaline.  There's one section of our episode where we thought it important to clarify what we're saying, as to out ears it sounds a little confusing. During our discussion about adrenaline, we state that both noradrenaline and adrenaline have the same affinity for beta-1 adrenoceptors. We then advise that the reason for the inotropic and chronotropic effects of adrenaline - not seen with noradrenaline - are because adrenaline has much greater affinity for beta-2 adrenaceptors than noradrenaline.Resources for today's episode:StatPearls:Inotropes and vasopressors by D. VanValkinburgh et al.Adrenergic Drugs by K. Farzam et al.LITFL:Inotropes, vasopressors and other vasoactive agents by C. NicksonMetaraminol by R. ButtnerPhenylephrine by C. NicksonNoradrenaline by C. NicksonAdrenaline by C. NicksonDeranged Physiology:Classification of inotropes and vasopressorsMetaraminolNoradrenalineAdrenalineDRUGBANK Online:MetaraminolEphedrinePhenylephrineNoradrenalineAdrenalineFeel free to email us at [email protected] if you have any questions, comments or suggestions. We love hearing from you! And don't forget to claim CPD for listening if you are a consultant or fellow. Log us as a learning session which you can find within the knowledge and skills division, and as evidence upload a screenshot of the podcast episode. Thanks for listening, and happy studying!