Sage- The kitchen herb that targets the same enzyme as Alzheimer's drugs episode artwork

EPISODE · Apr 28, 2026 · 5 MIN

Sage- The kitchen herb that targets the same enzyme as Alzheimer's drugs

from NutraSift: The nutraceutical innovation podcast · host Siftlink SA

Sage inhibits acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE), the same enzyme targets as donepezil (Aricept) and rivastigmine (Exelon), the standard-of-care Alzheimer's drugs. A single-dose RCT in healthy adults showed significant improvement in memory and attention after sage extract. The name "Salvia" comes from Latin "salvare" to save/heal. A kitchen spice has a drug-level mechanism for cognitive preservation.Publications of interest:https://pubmed.ncbi.nlm.nih.gov/18350281/, https://pubmed.ncbi.nlm.nih.gov/12605619/, https://pmc.ncbi.nlm.nih.gov/articles/PMC6493168/

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