Sarcomas and Bone Health: When a Painless Lump is More Than Just a Mass episode artwork

EPISODE · Aug 20, 2026 · 34 MIN

Sarcomas and Bone Health: When a Painless Lump is More Than Just a Mass

from Fit As A Fiddle · host Dr. Sneha Gazi

This episode of Fit As A Fiddle features Dr. Ilya Iofin, Chief of Orthopedic Oncology at Mount Sinai Hospital. We explore the complex world of cancer, focusing on the specialized treatment of rare soft tissue and bone sarcomas. Dr. Iofin explains that cancer is not one disease, but a diverse group of conditions that can present and behave differently based on specific mutations and the individual patient. He also shares insights into navigating uncertain prognoses and making difficult decisions about limb-sparing surgery versus amputation.A major focus is soft tissue sarcomas, with only about 15,000 cases diagnosed annually in the United States. Dr. Iofin explains how to distinguish a common benign mass, such as a lipoma, from a potentially dangerous sarcoma. Listeners will learn the warning signs that require prompt medical attention: a mass larger than two inches, located deep within the muscle, or actively growing, even if it is painless. The discussion also covers metastatic bone disease and how unexplained fractures without significant trauma, such as a femur breaking while walking, may signal an underlying tumor.Finally, we explore the evolving role of technology in medicine. Dr. Iofin discusses how artificial intelligence can help summarize medical literature, while emphasizing the need for fact-checking. He also explains why the critical thinking and highly skilled hands-on work of human surgeons will not be replaced by machines anytime soon.Click here and use your exclusive 20% listener discount (Code: Fit20) to enroll in Master Your Pelvic Floor, our signature self-paced course that will change the way you understand and care for your body.

Episode metadata supplied by the publisher feed · Published Aug 20, 2026

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This episode of Fit As A Fiddle features Dr. Ilya Iofin, Chief of Orthopedic Oncology at Mount Sinai Hospital. We explore the complex world of cancer, focusing on the specialized treatment of rare soft tissue and bone sarcomas. Dr. Iofin explains that cancer is not one disease, but a diverse group of conditions that can present and behave differently based on specific mutations and the individual patient. He also shares insights into navigating uncertain prognoses and making difficult decisio...

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Sarcomas and Bone Health: When a Painless Lump is More Than Just a Mass

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