Séminaire - Marco Cosentino-Lagomarsino : Using Mathematical Models and Model-Guided Data Analysis to Understand Cellular Decisions to Grow and Progress the Cell Cycle

Jean-François JoannyMatière molle et biophysiqueCollège de FranceAnnée 2023-2024Séminaire - Marco Cosentino-Lagomarsino : Using Mathematical Models and Model-Guided Data Analysis to Understand Cellular Decisions to Grow and Progress the Cell CycleMarco Cosentino-LagomarsinoProfesseur, IFOM, Milan, ItalieRésuméThis seminar investigates the mechanisms guiding cell growth and cell cycle progression decisions, using insights from single-cell dynamics. By utilizing advanced modeling and data-analysis techniques, I will address the stochasticity, homeostatic controls, and decisional logic of these fundamental biological processes, using data from E. coli to mammalian cells, which are reshaping our current knowledge.