Semustine

rWotD Episode 3267: Semustine Welcome to random Wiki of the Day, your journey through Wikipedia's vast and varied content, one random article at a time.The random article for Tuesday, 14 April 2026, is Semustine.Semustine (1-(2-chloroethyl)-3-(trans-4-methylcyclohexyl)-1-nitrosourea, MeCCNU) is an alkylating nitrosourea compound used in chemotherapy treatment of various types of tumours. Due to its lipophilic property, semustine can cross the blood-brain barrier for the chemotherapy of brain tumours, where it interferes with DNA replication in the rapidly-dividing tumour cells.Semustine, just as lomustine, is administered orally.Evidence has been found that treatment with semustine can cause acute leukaemia as a delayed effect in very rare cases.This recording reflects the Wikipedia text as of 00:13 UTC on Tuesday, 14 April 2026.For the full current version of the article, see Semustine on Wikipedia.This podcast uses content from Wikipedia under the Creative Commons Attribution-ShareAlike License.Visit our archives at wikioftheday.com and subscribe to stay updated on new episodes.Follow us on Mastodon at @[email protected] check out Curmudgeon's Corner, a current events podcast.Until next time, I'm standard Joanna.