Sending datacenters into orbit | E2203 episode artwork

EPISODE · Nov 3, 2025 · 1H 17M

Sending datacenters into orbit | E2203

from This Week in Startups

👉 Register here to join the Founder University Japan kickoff! https://luma.com/cm0x90mk Today's show: *Starcloud has started sending AI chips into orbit. So is this where the datacenters the power AI will one day live? And does wifi work in the vacuum of space? We're asking the TOUGH questions. PLUS Jason and Alex are doing a deep dive on all this week's OpenAI news. Will they ever be able to pay back all these GPU purchases? What happens to the wider economy on the off chance they don't thrive? And what's with these rumors that ChatGPT has stopped giving medical or legal advice? All that and a look at TrustMRR (and why Jason advises you not to publicly share your Stripe), why Jason thinks Netflix should buy CNN, our hosts favorite Nazi hunter movies, and MORE. Timestamps: (0:00) Would you trust an LLM with your health? (2:08) Jason is bringing Founder U to The Kingdom AND Japan, so he's streaming in today live from Riyadh (4:20) Jason's guide to mastering international travel. (Shoutout to Whoop) (5:05) Are the big AI companies going TOO HARD on GPUs? And does this matter? (11:30) Squarespace - Use offer code TWIST to save 10% off your first purchase of a website or domain at https://www.Squarespace.com/TWIST (14:53) What happens to the wider economy if ChatGPT FAILS? Who gets hit by the "contagion"? (18:22) Jason's more likely scenario: What if ChatGPT becomes just one player in a larger market? (21:22) Pilot - Visit https://www.pilot.com/twist and get $1,200 off your first year. (23:57) ChatGPT can still give you general health and legal advice… just not a full diagnosis (31:57) Nexos.ai Stop Shadow AI in its tracks with the unified platform for secure AI adoption and productivity. Try it with a free 14-day trial at https://nexos.ai/twist. (33:09) TrustMRR and startups sharing their Stripe data… Why Jason says total transparency might be too much (38:35) We're really sending datacenters to space! Starcloud made it happen. (41:02) Does wifi work in space? A TWiST investigation… (47:01) Checking in with Polymarkets on the NYC mayoral election and the government shutdown (53:09) Legal AI startup Legora (from Sweden) is now a unicorn… why this niche is growing so fast (58:14) Netflix wants to buy WBD… Here's why our hosts think they should keep CNN. (1:07:58) BUT WE DIGRESS: Lon and Jason's favorite Nazi hunter movies (1:10:25) Founder Q's! The best way to track runway and burn rate for early stage companies. Subscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.com Check out the TWIST500: https://www.twist500.com Subscribe to This Week in Startups on Apple: https://rb.gy/v19fcp Follow Lon: X: https://x.com/lons Follow Alex: X: https://x.com/alex LinkedIn: ⁠https://www.linkedin.com/in/alexwilhelm Follow Jason: X: https://twitter.com/Jason LinkedIn: https://www.linkedin.com/in/jasoncalacanis Thank you to our partners: Squarespace - Use offer code TWIST to save 10% off your first purchase of a website or domain at https://www.Squarespace.com/TWIST Pilot - Visit https://www.pilot.com/twist and get $1,200 off your first year. Nexos.ai Stop Shadow AI in its tracks with the unified platform for secure AI adoption and productivity. Try it with a free 14-day trial at https://nexos.ai/twist.

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Sending datacenters into orbit | E2203

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This episode was published on November 3, 2025.

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👉 Register here to join the Founder University Japan kickoff! https://luma.com/cm0x90mk Today's show: *Starcloud has started sending AI chips into orbit. So is this where the datacenters the power AI will one day live? And does wifi work in the...

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