SENTIA - Buzz without the Booze? with Professor Nutt

Professor David Nutt was sacked by the UK government in 2009.  He was dismissed for reporting on the comparative harms of various drugs.  He claimed that ecstasy and LSD were less dangerous than alcohol which didn’t go down well as the government would not even acknowledge that alcohol was a drug in the first place!  In 2010 he published a landmark study in The Lancet – a study that ranked the harm done to users and society by a range of drugs.  His study put alcohol as number one – as more harmful to society than heroin and crack. Since leaving his government position Professor Nutt has been chairing Drugs Science, an NGO which does ground breaking research and provides independent, evidence based information on drugs. He’s been engaged in some fascinating research into alcohol, cannabis and psychedelics and for the last few years he’s been working on the development of a drink which has just been launched in the UK – called Sentia. Sentia is a new type of drink that doesn’t contain alcohol but aims to recreate its relaxing effects.  The blend of botanicals in Sentia does this by enhancing the activity of a neurotransmitter called GABA in the brain. Since recording the interview I’ve been lucky enough to sample Sentia and can report that not only is it delicious but it certainly does hit the spot and deliver a gentle buzz. I drank mine neat with lots of ice and enjoyed the spicy bitterness. Our lucky UK listeners will be able to order it right now and hopefully those of us in the rest of the world will get to sample it soon. In this Episode David’s interest in the effects of alcohol began during his career as a doctor. Like most doctors he would see patients who had been damaged by alcohol practically every day His goal has been to produce a drink which provides the buzz of alcohol without the harm Sentia replicates the positive effects of alcohol (sociability and relaxation) without the negative effects (aggression and dependence) Alcohol affects the brain a bit like a sledgehammer whereas Sentia is much more targetted The benefits of alcohol kick in after one or two drinks when it affects our GABA system which keeps the brain calm But if we push the dose up to more than two drinks then it affects other brain neurotransmitters and can lead to more-ishness, craving, binging, amnesia and hangovers So the Prof has found a way to minimise the unwanted effects. Sentia has been designed by a world-renowned team of botonists, innovators and scientists and it only targets the GABA system The fact that the herbs which have been used to create it can be found in nature and have been used for centuries means that it’s exempt from food safety testing. We talked about the fact that if alcohol was invented today it would never pass any of the rigourous food and drink safety tests which new products have to go through David reflected that alcohol seems to have a special and privileged status in the world and came up with the interesting comparison with the fact that guns seem to have a privileged place in US law He also pointed out that alcohol kills more people than guns each year! I googled this stat and discovered that 45,000 people died from gunshot wounds in 2020 whereas alcohol related deaths average around 140,000 a year in the US alone - 3M worldwide I asked the Prof if Sentia was safe for those of us in recovery – he made it clear that Sentia is not a medicine or a therapy However it will not create dependence and it will create a feeling of relaxation He sees it as a good alternative for people who are vulnerable to alcohol dependence At Tribe Sober we always say don’t drink alcohol free drinks if they trigger you so we would advise the same approach with Sentia The advantage of Sentia is that it’s not fake alcohol so probably is unlikely to trigger ex drinkers Sentia is available in the UK right now and you can read more about it on the website which is sentiaspirits.com  International distribution has its challenges but the first step may be to get it manufactured in the US and it could be sent as a concentrate to other countries – watch this space and we’ll keep you informed David took us through what happens in our brain when we drink alcohol First neuro transmitter to get hit is GABA – which makes us feel calmer, more relaxed and more like socialising Drinking more than a couple of glasses will trigger dopamine, a stimulant which will make us want more and is why we go on binges It also releases endorphins which contributes to addictiveness and lack of control Carry on drinking and we start to block the most important neuro transmitter - Glutamate which keeps us awake Glutamate is vital for consciousness and for laying down memories – so that’s why we get blackouts Blocking glutamate can lead to brain damage, withdrawal and is responsible for hangovers. I told the Prof about the 6 hour walking talking blackout that finally made me decide the quit He confirmed that blackouts are a huge red flag as there is a danger of brain damage We talked about the fact that deaths from liver damage in the UK have increased 3-fold in the last 30 years This is because the real price of alcohol has reduced to a third of what it was 30 years ago and availability has also increased dramatically If David was in government he would address this is by limiting availability and increasing taxation – these two measures would massively reduce the harms of alcohol More Info Subscription membership – you can join up HERE. To access our website, click HERE. If you would like a free copy of our “Annual Tracker” or our e-book 66 Days to Sobriety, please email [email protected]. If you would like to come to our Saturday afternoon Zoom Cafe as a guest and meet our community, just email [email protected].   Episode Sponsor This episode is sponsored by the Tribe Sober Membership Program.  If you want to change your relationship with alcohol then sign up today Read more about our program and subscribe HERE   Help us to Spread the Word! We made this podcast so that we can reach more people who need our help.  Please subscribe and share. If you enjoyed the podcast, then please leave us a 5-star review on Apple podcasts. Take a screenshot of your review, and DM it to Tribe Sober’s Instagram page – see PS below for instructions. We’ll send you something special to say thank you! We release a podcast episode every Saturday morning. You can follow Tribe Sober on Facebook, Twitter, TikTok and Instagram. You can join our private Facebook group HERE.   PS: How to Leave a Rating/Review in Apple Podcasts (on an iOS Device) Open the Podcasts app. EASY. Choose “Search” from the bottom row of icons and enter the name of the show (e.g. Recover Like a Mother) into the search field. Select the show under Shows (not under Episodes). Scroll down past the first few episodes until you see Ratings & Reviews. Click Write a Review underneath the displayed reviews from other listeners. You’ll then have the option to rate the show on a 5-star scale and write a review (you can rate without writing too but it’s always good to read your experience).