Sertraline Pharmacology

Sertraline is an SSRI. It has the highest potential to cause diarrhea of any SSRI. Sertraline is often called “Squirtraline” because of its potential to cause diarrhea. Sertraline has a much shorter half-life than fluoxetine. I discuss why that may be important in this podcast episode. I discuss the role of serotonin in platelet aggregation and how sertraline may affect this. I discuss important drug interactions on the podcast, be sure to check out my latest project which is a 200+ page book on managing drug interactions in primary care. Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!