Seth MacFarlane with Liz Gillies episode artwork

EPISODE · Oct 2, 2025 · 42 MIN

Seth MacFarlane with Liz Gillies

from Talkhouse Podcast · host Talkhouse

On this week’s Talkhouse Podcast we’ve got a pair of singers who both look to classic sounds for inspiration—and one of whom happens to also be the creator of one of the biggest animated shows ever. It’s Liz Gillies and Seth MacFarlane. Now even if you don’t know his name, you almost certainly know Seth MacFarlane’s work and voice. He’s the creator of the animated comedy Family Guy, which will enter its 24th season next year. He also co-created American Dad and The Cleveland Show, plus directed the movie Ted, among many other TV and film accomplishments. If that weren’t enough, MacFarlane has a second career as a musician, a pursuit born out of his love for big band music of days gone by: It’s not a lark or a joke, either. MacFarlane is a serious student of classic songwriters, which led to his ninth and latest album, Lush Life: The Lost Sinatra Arrangements. As that title suggests, MacFarlane was given access to a massive number of songs that had been arranged—often by big names—for Frank Sinatra to sing, but that had never actually been recorded. MacFarlane recruited an A-team to get them in shape, and he sang the hell out of them. Check out “I Never Felt This Way Before” right here. The other half of today’s conversation is MacFarlane’s friend and sometime musical collaborator Liz Gillies, who’s also a multi-hyphenate. You may have seen her on TV—going all the way back to Nickelodeon—in movies or on Broadway. She even provided voices on a couple of MacFarlane’s shows. But the two really found their working spark during the pandemic with Songs From Home, and that collaboration continued in 2023 with a holiday album called We Wish You The Merriest. As you’ll see from this conversation, Gillies and MacFarlane have a friendly rapport. In this lively conversation, Gillies grills MacFarlane on the origins of Lush Life, a fascinating story in which MacFarlane is deeply invested. They also talk about how Liz likes to go out when they’re on tour but Seth prefers the comfort of a hotel room, how to pronounce Rudolph the Red-Nosed Reindeer and more. Stick around for the end, when they get a little silly coming up with podcast names. Thanks for listening to the Talkhouse Podcast, and thanks to Seth MacFarlane and Liz Gillies for chatting. If you liked what you heard, please follow Talkhouse on your favorite podcasting platform. This episode was produced by Myron Kaplan, and the Talkhouse theme was composed and performed by The Range. See you next time! Find more illuminating podcasts on the ⁠⁠⁠Talkhouse Podcast Network⁠⁠⁠. Visit ⁠⁠⁠talkhouse.com⁠⁠⁠ to read essays, reviews, and more. Follow @talkhouse on ⁠⁠⁠Instagram⁠⁠⁠, ⁠⁠⁠Bluesky⁠⁠⁠, ⁠⁠⁠Twitter (X)⁠⁠⁠, ⁠⁠⁠Threads⁠⁠⁠, and ⁠⁠⁠Facebook⁠⁠⁠.

On this week’s Talkhouse Podcast we’ve got a pair of singers who both look to classic sounds for inspiration—and one of whom happens to also be the creator of one of the biggest animated shows ever. It’s Liz Gillies and Seth MacFarlane. Now even if you don’t know his name, you almost certainly know Seth MacFarlane’s work and voice. He’s the creator of the animated comedy Family Guy, which will enter its 24th season next year. He also co-created American Dad and The Cleveland Show, plus directed the movie Ted, among many other TV and film accomplishments. If that weren’t enough, MacFarlane has a second career as a musician, a pursuit born out of his love for big band music of days gone by: It’s not a lark or a joke, either. MacFarlane is a serious student of classic songwriters, which led to his ninth and latest album, Lush Life: The Lost Sinatra Arrangements. As that title suggests, MacFarlane was given access to a massive number of songs that had been arranged—often by big names—for Frank Sinatra to sing, but that had never actually been recorded. MacFarlane recruited an A-team to get them in shape, and he sang the hell out of them. Check out “I Never Felt This Way Before” right here. The other half of today’s conversation is MacFarlane’s friend and sometime musical collaborator Liz Gillies, who’s also a multi-hyphenate. You may have seen her on TV—going all the way back to Nickelodeon—in movies or on Broadway. She even provided voices on a couple of MacFarlane’s shows. But the two really found their working spark during the pandemic with Songs From Home, and that collaboration continued in 2023 with a holiday album called We Wish You The Merriest. As you’ll see from this conversation, Gillies and MacFarlane have a friendly rapport. In this lively conversation, Gillies grills MacFarlane on the origins of Lush Life, a fascinating story in which MacFarlane is deeply invested. They also talk about how Liz likes to go out when they’re on tour but Seth prefers the comfort of a hotel room, how to pronounce Rudolph the Red-Nosed Reindeer and more. Stick around for the end, when they get a little silly coming up with podcast names. Thanks for listening to the Talkhouse Podcast, and thanks to Seth MacFarlane and Liz Gillies for chatting. If you liked what you heard, please follow Talkhouse on your favorite podcasting platform. This episode was produced by Myron Kaplan, and the Talkhouse theme was composed and performed by The Range. See you next time! Find more illuminating podcasts on the ⁠⁠⁠Talkhouse Podcast Network⁠⁠⁠. Visit ⁠⁠⁠talkhouse.com⁠⁠⁠ to read essays, reviews, and more. Follow @talkhouse on ⁠⁠⁠Instagram⁠⁠⁠, ⁠⁠⁠Bluesky⁠⁠⁠, ⁠⁠⁠Twitter (X)⁠⁠⁠, ⁠⁠⁠Threads⁠⁠⁠, and ⁠⁠⁠Facebook⁠⁠⁠.

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Seth MacFarlane with Liz Gillies

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This episode is 42 minutes long.

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This episode was published on October 2, 2025.

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On this week’s Talkhouse Podcast we’ve got a pair of singers who both look to classic sounds for inspiration—and one of whom happens to also be the creator of one of the biggest animated shows ever. It’s Liz Gillies and Seth MacFarlane. Now even...

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