EPISODE · Jul 7, 2025 · 28 MIN
Sex meets immunology
from Microbial Mondays · host Merel Sijbranda and Alex Cloherty
Have you ever wondered how the immune system differs in men versus women? For instance, did you know that:Men get more viral, bacterial, parasitic and fungal infections, for example HIV and tuberculosisWomen are more prone to develop autoimmune diseases. For example, for an autoimmune disease called lupus, 9 out of 10 patients are womenWomen have stronger antibody responses to vaccination, and antibody responses to seasonal influenza vaccines are consistently at least twice as strong in women than menMen show an almost twofold higher risk of death from malignant cancer than women.In this new episode Alex and Merel discuss potential explanations for these facts, and the role for the immune system in these differences between men and women.In this episode we try to speak to the broad diversity of sex and gender in humans where possible and where the existing research permits. We hope to see increasing immunology research that captures this diversity in the future!
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Sex meets immunology
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