SHEDDING UGLY FAT WHILE PRESERVING MUSCLE
from Dr. Howard Smith Reports Hosted by Howard G. Smith MD, AM
Vidcast: https://www.instagram.com/p/DdVcmP3JDu5/ Current diet drugs, the GLP-1s, do help you lose weight, but they trigger muscle loss. The good news: nutritionists at UC-Berkeley now report that an old experimental compound, TOFA, coaxes your body to burn more energy without curbing your appetite. For you biochemists, TOFA stands for 5-tetradecyloxy-2-furoic acid. In a preclinical study published in the journal Science Advances, obese mice fed TOFA increase their energy expenditure by as much as 18%, lose body fat without significant loss of lean muscle, and show improvements in blood sugar, triglycerides and fatty liver disease. TOFA is not an appetite suppressant like the current diet drugs but rather activates metabolic pathways that encourage cells to burn fat and produce more energy. Combining TOFA with semaglutide or tirzepatide produced even greater weight loss and metabolic improvements in the mice than either treatment alone. *A final thought: TOFA has not yet been tested in humans. Its safety, effectiveness and its ability to drive weight loss in you and I while preserving our muscle masses is completely unknown. The references for this report are available on my website. #Obesity #WeightLoss #TOFA #Metabolism #HealthNews
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