EPISODE · Mar 12, 2026 · 13 MIN
瘦型MAFALD／MASH的诊断及治疗
from 消化肝病前沿资讯
本期播客聚焦瘦型代谢相关脂肪性肝病（MAFLD），打破“脂肪肝=肥胖”的固有认知。解析其定义、分型及与肥胖型相似的病理机制，揭示内脏脂肪、胰岛素抵抗等引发的恶性循环，剖析更差的预后与独特并发症，介绍六大类药物治疗进展及临床决策要点，强调生活方式干预的核心地位与未来研究方向，提醒公众警惕这一易被忽视的肝脏“隐形杀手”。00:06认识瘦型MAFLD基本概念00:50瘦型MAFLD的定义与分型01:57瘦型MAFLD的核心病理机制03:03内脏脂肪与疾病恶性循环04:07瘦型MAFLD的预后与并发症05:07PPAR激动剂等药物治疗进展06:01GLP-1激动剂的作用与副作用06:48SGLT2抑制剂的功效与注意点07:28维生素E及其他药物选择08:15临床诊断与一线治疗要点09:04生活方式干预目标与效果10:17二线药物治疗与证据局限11:10个体化治疗的重要性探讨12:11瘦型与肥胖型预后差异分析
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瘦型MAFALD／MASH的诊断及治疗
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