EPISODE · May 8, 2026 · 7 MIN
SHTG Digest — Friday May 8, 2026
from SHTG Daily Digest — Weiss Lab
No top-tier journal hits surfaced this week — showing the next-best tier — but the haul is unusually substantive: the first randomized evidence that an APOC3 siRNA (plozasiran) prevents recurrent pancreatitis in very severe hypertriglyceridemia, a major Hegele review repositioning ANGPTL3 as a remnant-cholesterol target, and new human data linking ANGPTL3/4/8 complexes to heart failure outcomes.
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SHTG Digest — Friday May 8, 2026
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