SHTG Digest — Wednesday April 29, 2026

A landmark week — the ACC/AHA released the first major U.S. dyslipidemia guideline since 2018, plozasiran's PALISADE post-hoc shows it prevents recurrent pancreatitis in very severe hypertriglyceridemia (and now has its first regulatory approval), and two new Nature Reviews Cardiology pieces frame the next phase for ApoC-III– and ANGPTL3-directed therapies.

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SHTG Digest — Wednesday April 29, 2026

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