EPISODE · Apr 30, 2026 · 20 MIN
SIBO, Gut Dysbiosis, and Elevated Oestrogen Levels
from This EndoLife · host Jessica Duffin
There are several reasons why SIBO and gut dysbiosis can influence endo growth, but today, I want to talk about just one of them, and that’s β-glucuronidase. References:1) https://pmc.ncbi.nlm.nih.gov/articles/PMC10416750/2) https://pmc.ncbi.nlm.nih.gov/articles/PMC12942269/3) https://pmc.ncbi.nlm.nih.gov/articles/PMC12942269/, https://www.thieme-connect.com/products/ejournals/abstract/10.1055/a-1402-6431, https://pmc.ncbi.nlm.nih.gov/articles/PMC3768652/4) https://pubmed.ncbi.nlm.nih.gov/33839907/5) https://academic.oup.com/humupd/article/28/1/92/6412766, https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0261362, https://www.mdpi.com/1422-0067/24/22/16301, https://www.mdpi.com/1467-3045/47/7/502, https://www.frontiersin.org/journals/microbiology/articles/10.3389/fmicb.2024.1363455/full, https://www.mdpi.com/2077-0383/12/22/71766) https://www.fertstert.org/article/S0015-0282(23)00241-8/fulltext7) https://www.mdpi.com/2077-0383/12/22/7176, https://academic.oup.com/humupd/article/28/1/92/6412766, https://www.maturitas.org/article/S0378-5122(17)30650-3/fulltext, https://e-jmm.org/pdf/10.6118/jmm.240248) https://www.researchgate.net/publication/222032497_Dietary_fiber_and_activity_of_intestinal_tissue_ss-glucuronidase_in_rats, https://www.clinicalnutritionopenscience.com/article/S2667-2685(25)00039-7/pdf, https://pmc.ncbi.nlm.nih.gov/articles/PMC2858007/9) https://pmc.ncbi.nlm.nih.gov/articles/PMC6474371/, https://pubmed.ncbi.nlm.nih.gov/17474873/, https://www.clinicalnutritionopenscience.com/article/S2667-2685(25)00039-7/pdf, https://www.sciencedirect.com/science/article/abs/pii/S027153171500315210) https://www.sciencedirect.com/science/article/pii/S0022316622105158, https://www.cancernetwork.com/view/high-fat-diet-not-associated-increased-estrogen-postmenopausal-women11) https://www.clinicalnutritionopenscience.com/article/S2667-2685(25)00039-7/pdf12) https://pmc.ncbi.nlm.nih.gov/articles/PMC10416750/, https://pubmed.ncbi.nlm.nih.gov/32249416/13) https://pmc.ncbi.nlm.nih.gov/articles/PMC10416750/14) https://pmc.ncbi.nlm.nih.gov/articles/PMC10416750/15) https://pmc.ncbi.nlm.nih.gov/articles/PMC10416750/, https://pubmed.ncbi.nlm.nih.gov/33733438/, https://www.sciencedirect.com/science/article/pii/S014181301939277316) https://pubmed.ncbi.nlm.nih.gov/12197785/, https://pubmed.ncbi.nlm.nih.gov/2346674/17) https://pubmed.ncbi.nlm.nih.gov/33733438/18) https://www.sciencedirect.com/science/article/abs/pii/S0308814623016242, https://www.theendobellycoach.com/podcast/phgg-endo-belly-sibo-ibs19) https://www.tandfonline.com/doi/pdf/10.1271/bbb.58.136420) https://journals.lww.com/co-gastroenterology/fulltext/2025/11000/modern_concepts_of_small_intestinal_bacterial.5.aspx21) https://www.monashfodmap.com/blog/getting-enough-fibre/23) https://www.theendobellycoach.com/podcast/low-fodmap-diet-endometriosis, https://www.theendobellycoach.com/podcast/low-fodmap-diet-endometriosis-siboNeed more help or want to learn how to work with me?Ways to work with me:One to one coaching info and application Endo Sessions: Single and mini-package one to one endo coachingSIBO Sessions: Single and mini-package one to one SIBO coachingLive and Thrive with Endo 2.0 DIY online courseMasterclasses in endo nutrition, surgery prep and recovery and pain reliefThis EndoLife, It Starts with Breakfast digital cookbookAffiliate PartnershipsmBIOTA - You can learn more about the formula at mbiota.com and get 20% off with code ENDOLIFE (all caps). Code is valid for the two-week protocol and until June 14th.Mira - Mira is an at-home hormone testing device for every day use. Use this link and code 2DUFFJESS20 to get 20% off the device and any future wand orders.Tempdrop- Track fertility effortlessly with Tempdrop’s Wearable Sensor. Get 15% off with code: ENDOLIFEFree resources:This podcast! Endometriosis Net ColumnEndometriosis News ColumnSubstack Instagram
What this episode covers
There are several reasons why SIBO and gut dysbiosis can influence endo growth, but today, I want to talk about just one of them, and that’s β-glucuronidase. References:1) https://pmc.ncbi.nlm.nih.gov/articles/PMC10416750/2) https://pmc.ncbi.nlm.nih.gov/articles/PMC12942269/3) https://pmc.ncbi.nlm.nih.gov/articles/PMC12942269/, https://www.thieme-connect.com/products/ejournals/abstract/10.1055/a-1402-6431, https://pmc.ncbi.nlm.nih.gov/articles/PMC3768652/4) https://pubmed.ncbi.nlm.nih.gov/33839907/5) https://academic.oup.com/humupd/article/28/1/92/6412766, https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0261362, https://www.mdpi.com/1422-0067/24/22/16301, https://www.mdpi.com/1467-3045/47/7/502, https://www.frontiersin.org/journals/microbiology/articles/10.3389/fmicb.2024.1363455/full, https://www.mdpi.com/2077-0383/12/22/71766) https://www.fertstert.org/article/S0015-0282(23)00241-8/fulltext7) https://www.mdpi.com/2077-0383/12/22/7176, https://academic.oup.com/humupd/article/28/1/92/6412766, https://www.maturitas.org/article/S0378-5122(17)30650-3/fulltext, https://e-jmm.org/pdf/10.6118/jmm.240248) https://www.researchgate.net/publication/222032497_Dietary_fiber_and_activity_of_intestinal_tissue_ss-glucuronidase_in_rats, https://www.clinicalnutritionopenscience.com/article/S2667-2685(25)00039-7/pdf, https://pmc.ncbi.nlm.nih.gov/articles/PMC2858007/9) https://pmc.ncbi.nlm.nih.gov/articles/PMC6474371/, https://pubmed.ncbi.nlm.nih.gov/17474873/, https://www.clinicalnutritionopenscience.com/article/S2667-2685(25)00039-7/pdf, https://www.sciencedirect.com/science/article/abs/pii/S027153171500315210) https://www.sciencedirect.com/science/article/pii/S0022316622105158, https://www.cancernetwork.com/view/high-fat-diet-not-associated-increased-estrogen-postmenopausal-women11) https://www.clinicalnutritionopenscience.com/article/S2667-2685(25)00039-7/pdf12) https://pmc.ncbi.nlm.nih.gov/articles/PMC10416750/, https://pubmed.ncbi.nlm.nih.gov/32249416/13) https://pmc.ncbi.nlm.nih.gov/articles/PMC10416750/14) https://pmc.ncbi.nlm.nih.gov/articles/PMC10416750/15) https://pmc.ncbi.nlm.nih.gov/articles/PMC10416750/, https://pubmed.ncbi.nlm.nih.gov/33733438/, https://www.sciencedirect.com/science/article/pii/S014181301939277316) https://pubmed.ncbi.nlm.nih.gov/12197785/, https://pubmed.ncbi.nlm.nih.gov/2346674/17) https://pubmed.ncbi.nlm.nih.gov/33733438/18) https://www.sciencedirect.com/science/article/abs/pii/S0308814623016242, https://www.theendobellycoach.com/podcast/phgg-endo-belly-sibo-ibs19) https://www.tandfonline.com/doi/pdf/10.1271/bbb.58.136420) https://journals.lww.com/co-gastroenterology/fulltext/2025/11000/modern_concepts_of_small_intestinal_bacterial.5.aspx21) https://www.monashfodmap.com/blog/getting-enough-fibre/23) https://www.theendobellycoach.com/podcast/low-fodmap-diet-endometriosis, https://www.theendobellycoach.com/podcast/low-fodmap-diet-endometriosis-siboNeed more help or want to learn how to work with me?Ways to work with me:One to one coaching info and application Endo Sessions: Single and mini-package one to one endo coachingSIBO Sessions: Single and mini-package one to one SIBO coachingLive and Thrive with Endo 2.0 DIY online courseMasterclasses in endo nutrition, surgery prep and recovery and pain reliefThis EndoLife, It Starts with Breakfast digital cookbookAffiliate PartnershipsmBIOTA - You can learn more about the formula at mbiota.com and get 20% off with code ENDOLIFE (all caps). Code is valid for the two-week protocol and until June 14th.Mira - Mira is an at-home hormone testing device for every day use. Use this link and code 2DUFFJESS20 to get 20% off the device and any future wand orders.Tempdrop- Track fertility effortlessly with Tempdrop’s Wearable Sensor. Get 15% off with code: ENDOLIFEFree resources:This podcast! Endometriosis Net ColumnEndometriosis News ColumnSubstack Instagram
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SIBO, Gut Dysbiosis, and Elevated Oestrogen Levels
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