Silybin A and Silybin B: same name, different molecule, different potency

Silymarin contains two isomers of silybin (A and B) with different 3D configurations and different biological activity. No commercial standardization distinguishes between them. A product optimized for the more potent isomer on metabolic targets would be a genuinely novel ingredient from a plant used for 2,000 years.Publications of interest:https://pubmed.ncbi.nlm.nih.gov/22224281/https://pubmed.ncbi.nlm.nih.gov/34360650/https://pmc.ncbi.nlm.nih.gov/articles/PMC6150307/