Sirona Dx: Spatial Biology and Single-Cell Analytics in Clinical Programs | Stories in Life Sciences

Sirona Dx pioneered the first commercial spatial-omics CRO service in 2018, giving biopharma access to spatial biology and single-cell analytics at the depth and regulatory rigor clinical programs require.In this episode of Stories in Life Sciences by MedAxis AI, Christopher Wilson sits down with Nasry Yassa, PhD, CEO, and Andrew Brown, PhD, Chief Commercial Officer of Sirona Dx, to explore how they built a technical CRO from scratch in Portland, Oregon, and what it takes to bring spatial biology into clinical trial programs.Sirona Dx operates as a GCLP and CLIA accredited laboratory and has taken a technology-agnostic approach that lets biopharma clients access the right platform for their program rather than being locked into a single vendor. Their biomarker rescue work, helping a pharma client whose program had produced no useful data advance to Phase 2, is a clear example of what that approach makes possible.We cover:How spatial biology and single-cell analytics differ from traditional biomarker methodsWhy pharma companies need a technology-agnostic CRO rather than a lab tied to one platformThe biomarker rescue: how Sirona Dx helped a pharma client advance to Phase 2 after producing no useful dataBuilding a technical team where scientists own equity and are driven by the scienceWhat it means to operate as a GCLP and CLIA accredited laboratory in a clinical contextHow Oregon's talent pool and Obi Innovation Hub infrastructure enabled growth without outside investmentThe next chapter: bringing spatial biology technologies to individual health and personal medicineWho this is for: biopharma founders, biotech executives, and life sciences operators working in immuno-oncology, cell therapy, or precision medicine who are evaluating CRO partnerships or thinking about the intersection of analytical science and clinical development.Guests: Nasry Yassa, PhD, Co-founder and CEO, Sirona Dx Andrew Brown, PhD, Co-founder and Chief Commercial Officer, Sirona Dx www.sironadx.comhttps://www.linkedin.com/in/nasry-yassa-phd-08433911https://www.linkedin.com/in/andrew-brown-0536755https://www.linkedin.com/company/sirona-dxHost:Christopher Wilson, Founder, MedAxis AIwww.medaxisai.org https://www.linkedin.com/in/christopher-wilson-medaxisaihttps://www.linkedin.com/company/medaxisai