Small Vessels, Big Trouble: How Vascular Disease Drives Dementia

In this 161st episode I unpack vascular dementia — what causes it, how it differs from (and often overlaps with) Alzheimer’s, and the brain and vascular mechanisms that drive cognitive decline. I review some common clinical features of vascular dementia, noteworthy MRI findings, and the major vascular and metabolic risk factors involved in the development and progression of this disease. This is a great example of how a preventative approach nowcan save a lot of trouble later!Citations:Homocysteine and vascular diseasehttps://pubmed.ncbi.nlm.nih.gov/8597939/Trimethylamine N-Oxide: The Good, the Bad andthe Unknownhttps://pmc.ncbi.nlm.nih.gov/articles/PMC5127123/