SNRI Antidepressants: Pharmacology Made Easy & Clinically Relevant

Discover serotonin-norepinephrine reuptake inhibitors (SNRIs)—safe, effective antidepressants for depression, anxiety, and pain syndromes. In this episode, you’ll learn:- How SNRIs work in the brain and differ from SSRIs, TCAs, and MAOIs- Key medications: venlafaxine, desvenlafaxine, duloxetine, milnacipran, levomilnacipran- Important side effects, including blood pressure changes and SIADH in older adults- Tips for safe switching, monitoring, and counseling patientsCompanion tables (indications, mechanisms, PK/PD, side-effect grid, and monitoring prompts) are available for download and teaching at https://www.thisiswhy.health/topics/pharmacology-review-snri-antidepressantsDisclaimer: This content is for educational purposes only and is not intended to provide medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have heard in this content.