Sometimes after I take my Mounjaro shot I see this at the spot I gave the shot. Anyone know why and the role of cortisol and stress hormones episode artwork

EPISODE · Jul 13, 2026 · 6 MIN

Sometimes after I take my Mounjaro shot I see this at the spot I gave the shot. Anyone know why and the role of cortisol and stress hormones

from CFP Weight Loss with Russell Clark · host Russell Clark, FNP-C

Sometimes after I take my Mounjaro shot I see this at the spot I gave the shot. Anyone know why and the role of cortisol and stress hormones Welcome to CFP Weight Loss. I'm Russell Clark, Nurse Practitioner. ... Someone in our community reached out with a question — and if you've wondered the same thing, I hope this helps. ... They asked: Sometimes after I take my Mounjaro shot I see this at the spot I gave the shot. Anyone know why and the role of cortisol and stress hormones ... Here is how I think through it. ... Understanding Injection Site Reactions with Mounjaro. ... Many adults in their late 40s and early 50s notice injection site reactions after their weekly Mounjaro (tirzepatide ) shot. These typically appear as redness, mild swelling, itching, or a small raised bump at the injection area—usually the abdomen, thigh, or upper arm. These reactions occur because Mounjaro is a large peptide molecule that triggers a localized immune response. Your body recognizes the medication as foreign and sends immune cells to the site, causing temporary inflammation. In my years helping patients through the CFP Weight Loss method, I've seen this in about 30-40% of new users, especially those with sensitive skin or higher baseline inflammation from conditions like type 2 diabetes. ... On the role of cortisol and stress hormones. Listen at CFP Weight Loss — community Q&A with Russell Clark, FNP-C. Read more: https://ask.cfpweightloss.com/sometimes-after-i-take-my-mounjaro-shot-i-see-this-at-the-spot-i-gave-the-shot-anyone-know-why-and-the-role-of-cortisol-and-stress-hormones

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Sometimes after I take my Mounjaro shot I see this at the spot I gave the shot. Anyone know why and the role of cortisol and stress hormones

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