SPECIAL EPISODE - Personalized Vaccines Combat Melanoma

from On Medical Grounds · host Jane Caldwell, PhD and Jeffrey Weber, MD, PhD

Today On Medical Grounds, we will be speaking with Dr. Jeffrey Weber of Isaac Perlmutter Cancer Center at NYU Langone Health. He is senior investigator of a phase two clinical trial for an mRNA melanoma vaccine. This vaccine has significantly reduced the recurrence of tumors in patients when combined with an immunotherapy drug. (00:48) Introducing Dr. Weber(01:38) Melanoma mRNA vaccine(04:14) How does an the vaccine work?(06:34) First randomized trial(07:38) Personalized medicine(09:28) Side effects(11:19) How is this vaccine similar to mRNA COVID vaccine?(12:52) Bedside to bench to bedside approach(14:34) How do patients get involved in clinical trials?(16:23) Definition of "cure"(17:52) Clinically meaningful endpoints(18:49) What's next for mRNA cancer vaccines?(19:38) Dr. Weber's personal cancer connection(20:22) What keeps Dr. Weber up at night?Visit us at OnMedicalGrounds.com for more podcasts or download our app! You can subscribe through your podcast platform, our website, or follow us on social media for podcast updates and medical news. Some of our podcasts offer FREE CME/CE credits.LinkTreeBlueSkyLinkedInInstagram

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How long is this episode of On Medical Grounds?

This episode is 22 minutes long.

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This episode was published on May 19, 2023.

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