Splice (2009) & Mimic (1997): Playing God with DNA

from Journey Through Sci-Fi: A Science Fiction Film Podcast

This week on Journey Through Sci-Fi, we're heading into murkier, creepier territory as we pair Mimic and Splice - two films that take mad science out of the lab and straight into body-horror nightmare fuel. Directed by Guillermo del Toro and Vincenzo Natali, they arrive from very different moments in sci-fi cinema. Mimic comes out of the late-90s creature-feature era, mixing practical effects with early CGI and big studio ambition. Splice, released over a decade later, taps into anxieties around gene splicing, biotech, and scientists who really should know better. Visit our website https://www.journeythroughscifi.com/ Email Us! Support the podcast on PATREON Add us on INSTAGRAM Find us on TIKTOK Like us on FACEBOOK Follow us on LETTERBOXD

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This episode is 1 hour and 14 minutes long.

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This episode was published on February 12, 2026.

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