EPISODE · Aug 6, 2026 · 19 MIN
Spongiform Thyroid Nodules
from Endocrine Deep Dives · host Gurbir Gill, MD
This episode explores spongiform thyroid nodules, a distinct sonographic pattern characterized by microcystic spaces that occupy more than half of the nodule volume. We break down the pathology of these colloid-filled hyperplastic follicles, which carry an exceptionally low malignancy risk of less than two percent. The discussion reviews classification across major guideline systems, conservative management thresholds, and why this highly reliable indicator of benign disease can independently rule out the need for fine-needle aspiration biopsy.
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Spongiform Thyroid Nodules
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