Squamous Cell Carcinoma of the Anal Canal — An Interview with Dr Marwan Fakih

Featuring an interview with Dr Marwan Fakih, including the following topics: Etiology and incidence of squamous cell carcinoma of the anal canal (SCAC) (0:00) Novel therapeutic strategies for the treatment of SCAC: Immunotherapy combinations and monitoring for recurrence with circulating tumor DNA assessment (4:37) Perspectives on the overall survival benefit observed with first-line retifanlimab and carboplatin/paclitaxel; potential for cure for patients with SCAC (8:22) Case: A woman in her mid 60s with recurrent unresectable metastatic SCAC receives retifanlimab with carboplatin/paclitaxel (16:56) Case: A woman in her mid 60s with recurrent unresectable metastatic SCAC receives single-agent immunotherapy (25:22) Case: A woman in her 60s with previously untreated metastatic SCAC receives chemotherapy and attains a complete response (29:21) Future directions for the treatment of SCAC (33:22) CME information and select publications