EPISODE · Jul 28, 2025 · 9 MIN

SSRI_SNSRI对术后疼痛管理的作用

Evaliation of intraoperative ketamine on the prevention of severe rebound pain upon cessation of peripheral nerve block: a prospective randomised, double-blind, placecbo-contrilled study. Br J Anaesth 2022; 128: 734-41 今天聊聊SSRI和SNRI在术后止痛上的效果，看看它们能否减少疼痛、降低慢性痛风险，还能少用点阿片类药物。这份来自日本大学医学部的研究汇总了24项试验，发现这类药尤其SNRI比如度洛西汀，在减轻短期和长期疼痛方面有效，而且不增加明显副作用。但问题是，这些微小的优势值得纳入个人化止痛方案吗？一起来探讨下吧02:01 虽然显著降低慢性疼痛风险，但S SRI SN R I的效果是否立竿见影？04:03 使用S N R I类药物作为常规止痛方案的一种：有效性与副作用分析06:03 术中与术后疼痛管理：S S R I S N R I的潜在优势与限制08:07 探索微小优势的代价：个体化术后疼痛管理中的权衡与抉择

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SSRI_SNSRI对术后疼痛管理的作用

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