Stanislav Grof on LSD Psychotherapy: Live Talk at Esalen, 1969 episode artwork

EPISODE · Nov 13, 2025 · 49 MIN

Stanislav Grof on LSD Psychotherapy: Live Talk at Esalen, 1969

from Voices of Esalen · host Esalen Institute

Stanislav Grof, born in Prague in 1931, was among the most influential figures in the early clinical use of LSD. Sometimes referred to as the Godfather of psychedelic psychotherapy, Grof was was trained as a Freudian psychoanalyst in Prague and was on track to follow in Freud's footsteps when his path was derailed by a powerful LSD session. He changed his life path and became one of the principal investigators of early psychedelic research behind the Iron Curtain, conducting systematic LSD psychotherapy at the Psychiatric Research Institute in Prague. Grof’s approach was largely psycholitic - meaning that in contrast to the single high-dose mystical model, he favored smaller doses that could be given consistently over the course of multiple sessions, thus emphasizing the very gradual revealing of the layered strata of the human unconscious. In this talk, Grof describes how the same substance can evoke vastly different experiences in different individuals, from childhood regression, to episodes resembling psychosis, to genuine mystical revelation. He offers accounts of patients reliving early developmental trauma and what appeared to be birth agony, followed by experiences of renewal or “rebirth.” He also touches on the emergence of archetypal and transpersonal imagery in advanced stages of therapy, giving insight into the collective and cosmic dimensions of mind. Here’s the brilliant Stan Grof in 1969 at Esalen institute. Photo by Joyce Lyke

Stanislav Grof, born in Prague in 1931, was among the most influential figures in the early clinical use of LSD. Sometimes referred to as the Godfather of psychedelic psychotherapy, Grof was was trained as a Freudian psychoanalyst in Prague and was on track to follow in Freud's footsteps when his path was derailed by a powerful LSD session. He changed his life path and became one of the principal investigators of early psychedelic research behind the Iron Curtain, conducting systematic LSD psychotherapy at the Psychiatric Research Institute in Prague. Grof’s approach was largely psycholitic - meaning that in contrast to the single high-dose mystical model, he favored smaller doses that could be given consistently over the course of multiple sessions, thus emphasizing the very gradual revealing of the layered strata of the human unconscious. In this talk, Grof describes how the same substance can evoke vastly different experiences in different individuals, from childhood regression, to episodes resembling psychosis, to genuine mystical revelation. He offers accounts of patients reliving early developmental trauma and what appeared to be birth agony, followed by experiences of renewal or “rebirth.” He also touches on the emergence of archetypal and transpersonal imagery in advanced stages of therapy, giving insight into the collective and cosmic dimensions of mind. Here’s the brilliant Stan Grof in 1969 at Esalen institute. Photo by Joyce Lyke

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Stanislav Grof on LSD Psychotherapy: Live Talk at Esalen, 1969

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This episode was published on November 13, 2025.

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Stanislav Grof, born in Prague in 1931, was among the most influential figures in the early clinical use of LSD. Sometimes referred to as the Godfather of psychedelic psychotherapy, Grof was was trained as a Freudian psychoanalyst in Prague and was...

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