🎧 START pod: Arvid Gollwitzer, Co-Founder, Anto Bio: “A Foundation Model for Microbial Communities”

A drug was approved in ChinaThen it failed clinical trials in the USNo one could figure out whyThe answer was hiding in the gut microbiomeAnto Bio’s model helped identify it99% of the genes in your body aren't yours They belong to your microbiomeOver two-thirds of drugs are heavily affected by how your gut processes themBut the microbiome data was too noisy. Too messy. Petabytes of it just sitting thereAnto Bio's mission: make the gut microbiome computable for the first timeThey're building foundation models that help pharma design drugs that work for more people🎙️ Arvid Gollwitzer, Co-Founder, Anto Bio on Fondo START pod1:18 What Anto Bio is building and why it's novel2:10 Why this didn't exist before3:05 99% of your genes aren't yours4:00 Why pharma ignoring the microbiome is a huge problem5:04 The microbiome is modifiable6:30 Modeling microbiome differences across populations7:00 Drug approved in China, failed in the US, and how Anto found out why8:02 How many drugs are affected by microbiome metabolism10:00 GLP-1s and the gut microbiome connection12:42 The biggest unsolved variable in drug developmentLearn more at www.anto.bio