Stem Cells: From Cancer Vaccines to Space Research

In today’s episode, we will talk about new research on the use of an induced pluripotent stem cell-based vaccine to potentially protect against pancreatic cancer. This approach takes advantage of shared antigens between stem cells and pancreatic cancer cells and seeks to exploit them for clinical benefit. We will talk with the authors of this new research published in Stem Cell Reports on why they decided to pursue this approach, the background behind it, and whether this approach could work for other types of cancers. We also discuss some of Dr. Wu's other work, including research on stem cells in microgravity. Show NotesGuestsJoseph Wu, MD, PhD Director of the Stanford Cardiovascular Institute,  US Website: http://med.stanford.edu/wulab.htmlXiaoming Ouyang, PhD, Postdoctoral Scholar, Wu Laboratory, Stanford University, US Website: https://www.researchgate.net/profile/Xiaoming-OuyangHostMartin Pera, PhD – Editor-in-Chief, Stem Cell Reports and The Jackson LaboratoryWebsite: https://www.jax.org/research-and-faculty/faculty/martin-peraTwitter: @martinperaJAXSupporting DocumentsAnti-Tumor Effects of iPSC-Based Cancer Vaccine in Pancreatic Cancerhttps://www.cell.com/stem-cell-reports/fulltext/S2213-6711(21)00199-5About Stem Cell ReportsStem Cell Reports is the Open Access journal of the International Society for Stem Cell Research for communicating basic discoveries in stem cell research, in addition to translational and clinical studies. Stem Cell Reports focuses on original research with conceptual or practical advances that are of broad interest to stem cell biologists and clinicians.Twitter: @stemcellreportsAbout ISSCRWith nearly 4,000 members from more than 65 countries, the International Society for Stem Cell Research is the preeminent global, cross-disciplinary, science-based organization dedicated to stem cell research and its translation to the clinic. The ISSCR mission is to promote excellence in stem cell science and applications to human health.Twitter: @ISSCR AcknowledgementsISSCR StaffKeith Alm, Chief Operating OfficerBethany Almon, Senior Manager of Integrated MarketingYvonne Fisher, Managing Editor, Stem Cell ReportsKym Kilbourne, Director of Media and Strategic CommunicationsJack Mosher, Senior Manager of Scientific AffairsNancy Witty, Chief Executive OfficerVoice WorkJulie PerlinBen SnitkoffMusic@Konovalov