Sticking Safely: Medical PSAs, Biocompatibility, and ISO 10993

Why must a medical adhesive stick—and then let go—without harming the skin? In this episode of Adhesion Matters, we dig into the science—and the sticky business—behind pressure-sensitive adhesives (PSAs) designed for everything from surgical dressings and wearables to wound care patches. We compare key chemistries—silicones, acrylics, and hydrogels—and show how each serves specific medical purposes like temperature resistance, conformability, or moisture management.We break down the rigorous ISO 10993 standards for biocompatibility, including critical tests for cytotoxicity, sensitization, and irritation. We also spotlight how companies like Dow and Henkel navigate those standards while enabling modern device manufacturing through UV-cure imaging and fast assembly.Finally, we look ahead to what’s next: from bioresorbable adhesives and smart, medication-releasing patches to PFAS- and solvent-free formulations—showing how the next wave of medical adhesives aims to stick safely while innovating boldly.Whether you're a materials engineer, regulatory specialist, or just fascinated by where adhesives intersect with healthcare, this episode reveals how smart chemistry keeps us safer—and more comfortable—on the skin.