STOP AGING WITHOUT CUTTING CALORIES?

Vidcast: https://www.instagram.com/p/DdUXv9uPn_O/ Yale researchers find that one of the unexpected byproducts of dieting is the reduction of agents that degrade our tissues. That process is under the control of the immune system component C3. This protein normally increases with age and is known to increase the inflammation that degrades our tissues. The New Haven immunobiologists studied 42 participants in the so-called CALERIE trial. These subjects reduced their caloric intake by 11 to 14% over a two year period. Blood testing revealed that their C3 levels diminished in association with weight loss. Studying this phenomenon in mice, the researchers found that C3 levels increase with age and that the agent is produced by scavenger white cells, macrophages, that proliferate fat tissue. When researchers C3 activation is blocked, the mice develop less age-related inflammation. * Unfortunately, there is currently no C3-blocking drug that can make you live longer, so don’t start searching the web for one. Yale researchers at on the hunt. Their studies do identify a potentially important biological pathway through which moderate calorie restriction may promote healthier aging. References on my website. #Aging #Longevity #CalorieRestriction #Inflammation #MedicalResearch