Stop Financial Leakage: The Truth About 340B TPA Auto-Ordering | Lyssa Limbrecht-Mosh

What is a 340B contract pharmacy program? A 340B contract pharmacy program is an operational partnership where a covered entity utilizes an external pharmacy to dispense discounted outpatient drugs to eligible patients. To maintain compliance and profitability, entities must rigorously manage inventory, dispensing fees, and TPA audits.The friction between covered entities and contract pharmacies is costing the 340B ecosystem millions. In this episode of 340B Pulse, Mohammad Atif and Hassan sit down with Lyssa Limbrecht-Mosh, founder of Optimal340B, to expose the operational realities of 340B pharmacy management. Lyssa breaks down why TPA auto-ordering systems trigger catastrophic inventory swell, how to structure fair dispensing fees, and why auditing uncaptured claims is the fastest way to recover lost revenue. We also discuss the looming threat of the Maximum Fair Price (MFP) regulations and the controversial shift toward a rebate model.00:00 - Introduction to 340B Pulse 04:49 - Lyssa's Journey into 340B Compliance 06:41 - What Defines a Healthy Contract Pharmacy? 08:19 - The Disconnect in Healthcare Reimbursement 11:34 - The Danger of TPA Auto-Ordering & Inventory Swell 18:22 - Structuring Fair Pharmacy Dispensing Fees 21:32 - Real Example: Recovering $1.3 Million Through Audits 23:19 - 3 Immediate Steps to Improve Your 340B Program 25:03 - The Role of AI and Custom Technology in 340B 27:24 - Future Threats: MFP and the 340B Rebate Model 29:20 - How to Connect with Optimal340BHow do you prevent 340B inventory swell? To prevent 340B inventory swell, covered entities must communicate with their contract pharmacies, avoid rigid auto-ordering for low-volume specialty drugs, and allow pharmacies visibility into replenishment schedules.Why are 340B dispensing fees important? 340B dispensing fees compensate the contract pharmacy for the operational burden of managing dual inventories and processing complex 340B claims, ensuring the partnership remains financially viable for the pharmacy.What is the 340B rebate model? The 340B rebate model is a proposed system where covered entities purchase drugs at full wholesale acquisition cost (WAC) and subsequently request a rebate from the manufacturer, significantly impacting cash flow.340B #HealthcareCompliance #PharmacyOperations #ContractPharmacy #NorthArc #HealthcareTechnology #340BAudits #Optimal340B #HealthTech