Stopping Prolia and Increased Fracture Risk

In this episode, Dr. Doug discusses the popular drug Prolia (Denosumab) used for the treatment of osteoporosis. He focuses on the risk of fracture after stopping the drug and addresses the fear surrounding it. Dr. Doug presents research from the FREEDOM trial, which showed a reduction in vertebral fractures with Prolia but also a reduction in bone building. He then discusses the 10-year data from the trial, which showed an increased risk of vertebral fractures after discontinuing the drug. Dr. Doug reassures listeners that with a solid plan and monitoring, the risk can be managed.