Study Shows APOE Gene Affects Hispanic Populations’ Risk of Cognitive Decline Differently to Non-Hispanic Populations

from Dementia Matters · host Wisconsin Alzheimer‘s Disease Research Center

The APOE gene is recognized as a significant genetic risk factor for cognitive decline, with different alleles, like APOE e2, being seen as protective against decline and others, like APOE e4, indicating an increased risk for cognitive decline. However, new studies are looking at whether these trends are universal across different racial and ethnic groups. Dr. Cally Xiao joins the podcast to discuss her study, which focuses on how different APOE alleles affect risk for Alzheimer’s disease within Hispanic populations compared to non-Hispanic populations. Guest: Cally Xiao, PhD, Project Specialist, Global Alzheimer’s Association Interactive Network, Laboratory of Neuro Imaging, University of Southern California Show Notes Follow Dr. Xiao on Twitter. Learn more about GAAIN on their website or on Twitter. Read more about the study, “Comparison of genetic and health risk factors for mild cognitive impairment and Alzheimer's disease between Hispanic and non-Hispanic white participants,” online through the journal Alzheimer’s and Dementia. Listen to Sarah Biber’s episode, “The Future Of Sharing And Accessing Alzheimer’s Disease Data,” on our website, Spotify, Apple Podcasts, Podbean, and all major podcast platforms. Connect with us Find transcripts and more at our website. Email Dementia Matters: [email protected] Follow us on Facebook and Twitter. Subscribe to the Wisconsin Alzheimer’s Disease Research Center’s e-newsletter.

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This episode was published on July 12, 2023.

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