Summary of the February 3, 2010 issue of JNCI

Issue 3 of the Journal of the National Cancer Institute includes a commentary and article that summarizes the latest research questions that came out of last fall's NIH state-of-the-science conference on ductal carcinoma in situ. Also in this issue, researchers found that a Chinese herbal product is associated with the risk of urinary tract cancer. Other studies involve SNPs in C-reactive protein and cancer risk and a nationwide cohort study that investigated sexual defects in boys and testicular cancer risk. Also, a commentary looked at design issues of randomized clinical trials with biomarkers. And in the issue's last study, researchers investigated risk of colorectal, endometrial, and Lynch syndrome cancers for people with the germ-line MSH6 mutation.