Summary of the January 19, 2010 issue of JNCI

Issue 2 of the Journal of the National Cancer Institute includes a review on cancer care and cost-effectiveness. Researchers provide a systematic overview of cost utility analysis in oncology. Also, an article and accompanying editorial look at the prevalence of right-sided tumors vs. left-sided ones after colonoscopies. This issue also includes studies on the effects of gain-framed messages in smoking quitlines, the paracrine pathway and its role in pancreatic cancer cell invasion, and the risks of pancreatic cancer within families. And finally, in this issue's brief communication, researchers found that knockdown of transcription factor E2F1 reduces the invasive potential of melanoma cells.