Summary of the May 19 issue of JNCI

The May 19 online issue of the JNCI includes a study on the long-term risks of invasive cancer and recurrence of severe cervical intraepithelial neoplasia (CIN); a review of traditional and updated phase I trial designs; and a population-based study and editorial examining the association between lymphovascular invasion and high risk breast cancer. This issue also highlights data showing how four immunohistochemistry tests can distinguish between luminal A and B breast cancer subtypes; an extended follow-up examining occupational formaldehyde exposure and cancer risk; and a mouse study demonstrating that peroxisome proliferator-activated receptor-delta is involved in colon cancer formation.