Summary of the November 17, 2009 issue of JNCI

Issue 22 of the Journal of the National Cancer Institute includes a study and an editorial that looked at emerging patterns in smoking and bladder cancer. Also in this issue, researchers from Italy found that people living in volcanic areas may be a greater risk for thyroid cancer. Another study found that the small-molecule inhibitor nutlin-3 may be a viable treatment option for children with neuroblastoma with wild-type p53 activity. One study looked at recent changes in breast cancer incidence in Spain. And in this issue's commentary, a researcher argues that a relative utility curve is a simple method to evaluate risk prediction in a medical decision-making framework.