Surg: Peptic Ulcer Disease: Free MSRA Podcast episode artwork

EPISODE · May 20, 2025 · 16 MIN

Surg: Peptic Ulcer Disease: Free MSRA Podcast

from Pass the MSRA: Free Podcasts · host Pass the MSRA

🎙️ Deep Dive: Peptic Ulcer Disease (PUD) – Know the Pain, Master the Cause💊 A must-listen for MSRA revision and clinical clarity.Welcome back to The Deep Dive, where we turn complex clinical content into memorable revision gold. Today’s focus? Peptic Ulcer Disease (PUD) – those painful sores in the stomach or duodenum caused by H. pylori or common meds like NSAIDs. 🔬Let’s walk through symptoms, red flags, diagnosis, treatment, and everything you need for the MSRA.🧪 What Is PUD?Open sores in stomach (gastric) or duodenum (duodenal) liningCaused by imbalance between digestive acid and protective mucusOften due to Helicobacter pylori or NSAID useCan lead to pain, bleeding, or perforation🐛 H. pylori: The Main CulpritFound in ~95% of duodenal and 80% of gastric ulcersOther causes:NSAIDs, smoking, alcohol, stress, bile reflux, steroids, mucin changes🧠 Mnemonic: No Pain, So Bad, Always Stresses Mucin(NSAIDs, Pepsin, Smoking, Bile, Alcohol, Steroids, Stress, Mucin)📊 Risk Factors & EpidemiologyH. pylori, NSAIDs, alcohol, smoking, age >55, stress, FHxDuodenal ulcers more common than gastricGlobal incidence: ~0.1–0.2% per year🔥 Classic SymptomsBurning/gnawing epigastric pain• Worse with food = gastric ulcer• Improves with food = duodenal ulcerNausea, bloating, weight loss, melena, night pain🧠 Mnemonic: Gastric growls / Duodenal dissolves🩺 DifferentialsGORD, gastritis, dyspepsiaGallstones, pancreatitisGastric cancer, AAA, Crohn’sZollinger-Ellison, cardiac pain🔬 Key InvestigationsH. pylori tests: urea breath, stool antigen, serologyOGD = diagnostic + biopsyFBC for anaemia🧠 Alarm Symptoms Mnemonic: I Can't Wait To Please Even MoreI: Iron-deficiency anaemiaC: Chronic GI bleedingW: Weight lossT: Trouble swallowingP: Persistent vomitingE: Epigastric mass💊 Management SummaryEradicate H. pylori (PPI + 2 antibiotics)Stop NSAIDs where possibleStart PPI therapy ± H2 blockersLifestyle: quit smoking, reduce alcoholRepeat endoscopy for gastric ulcersEmergency endoscopy/surgery for bleeding/perforation⚠️ ComplicationsGI bleeding (melena, haematemesis)Perforation (surgical emergency)Gastric outlet obstructionRare cancer risk if H. pylori untreated📈 PrognosisExcellent with proper therapyMost heal in weeksRecurrence if H. pylori persists or NSAIDs continue📚 Peptic Ulcer Disease Revision Resources📝 Revision Notes:https://www.passthemsra.com/topic/peptic-ulcer-disease-revision-notes/🃏 Flashcards:https://www.passthemsra.com/topic/peptic-ulcer-disease-flashcards/📖 Accordion Q&A Notes:https://www.passthemsra.com/topic/peptic-ulcer-disease-accordion-qa-notes/🧠 Rapid Quiz:https://www.passthemsra.com/topic/peptic-ulcer-disease-rapid-quiz/📊 Quiz Platform:https://www.passthemsra.com/quizzes/peptic-ulcer-disease/🔑 Final Takeaway:PUD is common and treatable. Know the signs, test early, treat thoroughly.💡 Remember: Kill the bug. Stop the drugs. Suppress the acid.Explore more free and premium MSRA resources at:🌐 https://www.passthemsra.com🌐 https://www.freemssra.com#MSRA #PepticUlcerDisease #PUD #HPylori #MSRAQuiz #UpperGI #GastricUlcer #DuodenalUlcer #PassTheMSRA #GPExamPrep #DeepDivePodcast

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