EPISODE · Jun 24, 2026 · 34 MIN
Talk Liver To Me - Chasing the perfect SLD preclinical model
from EASL Podcasts
Steatotic liver disease (SLD) research relies heavily on preclinical models, yet no single model can fully capture the complexity of human disease. In this episode, we explore the new EASL position paper on preclinical SLD models. From MASLD and MetALD to organoids and precision-cut liver slices, we discuss the strengths, limitations, and translational relevance of today's most widely used models. How do we choose the right model, and are we any closer to finding the perfect one?Based on EASL position paper on preclinical models of steatotic liver diseaseHost: Rui Castro (University of Lisbon) Speakers: Mathias Heikenwälder (University of Tübingen) and Suchira Gallage (University of Tübingen)This episode is also available on EASL Campus: https://easlcampus.eu/tltm/episode-11This programme is intended for health care professionals only and is provided for educational purposes. EASL does not endorse or promote any medicinal products or medical devices. The views and opinions expressed are those of the speakers and do not necessarily reflect those of EASL. All declarations of conflicts of interest are listed on EASL Campus (https://easlcampus.eu/tltm/episode-11).EASL is not responsible for the accuracy of any translated versions of this podcast or of subtitles generated automatically by artificial intelligence.
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Steatotic liver disease (SLD) research relies heavily on preclinical models, yet no single model can fully capture the complexity of human disease. In this episode, we explore the new EASL position paper on preclinical SLD models. From MASLD and MetALD to organoids and precision-cut liver slices, we discuss the strengths, limitations, and translational relevance of today's most widely used models. How do we choose the right model, and are we any closer to finding the perfect one? Based on EAS...
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Talk Liver To Me - Chasing the perfect SLD preclinical model
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