Targeting 7-Ketocholesterol in Atherosclerosis with Matthew “Oki” O’Connor

What if cardiovascular disease wasn’t just about high cholesterol — but about a toxic, oxidized form that drives plaque buildup and cellular dysfunction?In this episode, hosts Raghav Sehgal and Macsue Jacques talk with Matthew “Oki” O’Connor, a leading researcher exploring how 7-ketocholesterol fuels atherosclerosis — and how a new therapeutic candidate could reverse aspects of this age-related disease.We dive into: 💡 What makes 7-ketocholesterol so harmful 🔬 How targeting it can transform foam cells back into healthy macrophages 💊 How this approach differs from statins and traditional lipid-lowering therapies 🌏 Early trials launching in Australia ⏳ The future of cardiovascular rejuvenation and healthy agingIf you’re interested in how cutting-edge science could reshape the fight against cardiovascular aging, this episode is for you.🎧 Listen now and explore how targeting oxidized cholesterol might help us decode longevity.