Test Before You Prescribe: A Low Testosterone Case Study Review episode artwork

EPISODE · Apr 7, 2026 · 51 MIN

Test Before You Prescribe: A Low Testosterone Case Study Review

from The DUTCH Podcast · host DUTCH Test

Send us Fan MailIn this episode, Dr. Jaclyn Smeaton and DUTCH Founder Mark Newman discuss a case study published in Integrative Medicine: A Clinician’s Journal in which Mark himself was the patient. The case covers the step-by-step hormonal and metabolic effects of using HCG to boost endogenous testosterone, revealing how increasing testosterone can cascade into elevated estrogen, impaired estrogen clearance, and strained methylation capacity. Their conversation also highlights: The benefits of combining serum testing and DUTCH testing to monitor dosing as well as metabolism, clearance, and methylation How methylation is affected by raising testosterone The value of tracking step-by-step supplementation plans with repeated testing The importance of baseline testing before beginning testosterone therapy An upcoming research publication that compares hormone testing methods for testosterone monitoring Read the DUTCH article and access the full IMCJ case report. Become a DUTCH Provider to see how the DUTCH Test can profoundly change the lives of your patients. 

Episode metadata supplied by the publisher feed · Published Apr 7, 2026

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Send us Fan Mail In this episode, Dr. Jaclyn Smeaton and DUTCH Founder Mark Newman discuss a case study published in Integrative Medicine: A Clinician’s Journal in which Mark himself was the patient. The case covers the step-by-step hormonal and metabolic effects of using HCG to boost endogenous testosterone, revealing how increasing testosterone can cascade into elevated estrogen, impaired estrogen clearance, and strained methylation capacity. Their conversation also highlights: ...

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Test Before You Prescribe: A Low Testosterone Case Study Review

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