EPISODE · Jun 26, 2025 · 33 MIN
The 4-Hour Sleepers Redefining Human Limits with Ying-Hui Fu of UCSF
from Business Trip · host Greg Kubin & Matias Serebrinsky
Matias and Greg interview Ying-Hui Fu, PhD, is a Professor of Neurology at UCSF and a world leader in the genetics of sleep. Her lab has discovered the first-known genes behind “natural short sleepers”. Her work bridges human genetics and neuroscience to uncover how to modulate sleep for brain health, aging, and neurodegenerative diseases.In this episode, we discuss:How some people thrive on 4–6 hours of sleep with rare genetic mutationsWhy sleep efficiency is more important than total hours sleptWhat short sleeper genes reveal about preventing Alzheimer’s and autismWhy current sleep research tools miss deeper brain activity patternsWhat’s next in sleep science with potential therapiesCredits:Created by Greg Kubin and Matias SerebrinskyHost: Matias Serebrinsky & Greg KubinProduced by Caitlin Ner & Nico V. Rey Find us at businesstrip.fm and psymed.venturesFollow us on Instagram and Twitter!Theme music by Dorian LoveAdditional Music: Distant Daze by Zack Frank
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Matias and Greg interview Ying-Hui Fu, PhD, is a Professor of Neurology at UCSF and a world leader in the genetics of sleep. Her lab has discovered the first-known genes behind “natural short sleepers”. Her work bridges human genetics and neuroscience to uncover how to modulate sleep for brain health, aging, and neurodegenerative diseases. In this episode, we discuss: How some people thrive on 4–6 hours of sleep with rare genetic mutationsWhy sleep efficiency is more important than total hour...
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The 4-Hour Sleepers Redefining Human Limits with Ying-Hui Fu of UCSF
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