The 5-Step Framework for AI Agents That Improve While You Sleep | E2269

This Week In Startups is made possible by: Quo - https://quo.com/TWiST LinkedIn Jobs - https://LinkedIn.com/twist Iru - https://iru.com/twist Plaud - https://Plaud.ai/twist Today's show: Google project manager Shubham Saboo is running 6 AI agents on a Mac Mini that handle all of his side business autonomously, from research, to social posts, to newsletters. He joins Jason and Lon to walk us through his 5-step framework for designing an efficient AI agent team: Start with one agent and onboard them like a new hire Stop Googling fixes; just ask your agent how to use it Put your agents on fixed schedules Add shared memory so you don't have to repeat yourself Let agents run self-reviews and rewrite their own instructions. Get the walkthrough to put this entire plan into practice on today's episode. PLUS fresh demos of the "Minecraft"-inspired virtual workspace MoltWorld and AgentMail, which is Gmail for your AI pals, and Jason explains the thinking behind his viral, controversy-stirring "don't talk to journalists" tweet. Follow Shubham: https://x.com/Saboo_Shubham_ "How I Built an Autonomous AI Agent Team That Runs 24/7" on X: https://x.com/Saboo_Shubham_/status/2022014147450614038?s=20 Follow Mike: https://x.com/mihalich1988 MoltWorld: https://moltworld.io/ Follow Haakam: https://x.com/haakamaujla AgentMail: https://www.agentmail.to/ Jason's post about talking to journalists: https://x.com/Jason/status/2037573025458016659 NYT responds: https://x.com/NYTimesPR/status/2037648223771263082 Translated Japanese tweets: https://x.com/melonneet40/status/2038020624015315289, https://x.com/rambling_28/status/2038041455999246422 Japanese people singing "Country Roads": https://x.com/harukaawake/status/2038081269830222259 Trailer for "Nuremberg" (now on Netflix in the US): https://www.youtube.com/watch?v=WvAy9C-bipY Timestamps: 0:00 Intro 1:24 Plaud: If your work depends on conversations — interviews, meetings, calls — you need a Plaud NotePin. You can check it out at https://Plaud.ai/twist and use code TWIST for 10% off! 3:05 We're Claw-pilled once again; it's an all AI Agent showcase 6:15 Google AI PM Shubham Saboo's Top 5 OpenClaw tips 10:14 Quo (formerly OpenPhone) gives you a clean, modern way to handle every customer call, text, and thread all in one place. Try it free at https://quo.com/TWiST. 13:26 Tip #1 — Onboard your agent like a new hire 17:31 Tip #2 — Talk to your agents constantly 19:02 Tip #3 — Put your agents on a schedule 19:51 LinkedIn Jobs - Hire right, the first time. Post your first job and get $100 off towards your job post at https://LinkedIn.com/twist. 23:41 Tip #4 — Add cross-agent memory 29:33 Tip #5 — Let your agents self-improve 29:51 Iru unifies identity, endpoint security, and compliance into one platform. TWiST listeners get 20% off when they book a demo at https://iru.com/twist! 34:03 Why Jason says founders should avoid journalists 38:24 How biased IS the New York Times? 47:02 DEMO: Co-founder Mike Nosov shows us MoltWorld 51:14 But what's the utility of this? 1:05:15 DEMO: Haakam Aujla presents AgentMail (YC S25) 1:09:59 How does AgentMail make money? 1:17:03 How Grok Translations are creating cross-cultural dialogue on X Subscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.com Check out the TWIST500: https://www.twist500.com Subscribe to This Week in Startups on Apple: https://rb.gy/v19fcp Follow Lon: X: https://x.com/lons Follow Alex: X: https://x.com/alex LinkedIn: ⁠https://www.linkedin.com/in/alexwilhelm Follow Jason: X: https://twitter.com/Jason LinkedIn: https://www.linkedin.com/in/jasoncalacanis Check out all our partner offers: https://partners.launch.co/ Great TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarland Check out Jason's suite of newsletters: https://substack.com/@calacanis