The ablative and immunomodulatory effects of histotripsy treatment in osteosarcoma

Joanne Tuohy, DVM, PhD from Virginia Tech and the Virgina-Maryland College of Veterinary Medicine will be sharing information about canine trials studying histotripsy as a novel tumor ablation modality for treating osteosarcoma. Histotripsy is a focused ultrasound tumor ablation technique that is non-invasive, non-ionizing and non-thermal, and it also has potential to induce immunomodulatory effects after tumor ablation. Histotripsy is capable of delivering highly precise tumor ablation and spares normal tissues adjacent to the ablation site. Histotripsy has exciting potential to serve as a non-surgical limb salvage treatment for osteosarcoma. Additionally, due to its immunomodulatory effects, histotripsy has potential to be synergistic with immunotherapies and increase the efficacy of immunotherapies in osteosarcoma. After a short presentation on this research, she will take questions from attendees. Share your questions in advance with us at [email protected].