The Adrenal-Gut-Immune Triangle: Why Your Gut Protocol Isn’t Working episode artwork

EPISODE · Mar 9, 2026 · 23 MIN

The Adrenal-Gut-Immune Triangle: Why Your Gut Protocol Isn’t Working

from The Goode Health: Functional Medicine, Longevity & Autoimmune

If you’ve changed your diet, taken the probiotics, followed the gut protocol, and you’re still not fully well, this episode explains why. In part two of our gut-immunity series, we introduce the adrenal-gut-immune Triangle and the missing link that keeps so many people stuck: chronic stress and HPA axis dysfunction.02:12 – What the Adrenal System Actually Is (HPA Axis Explained)04:25 – HPA Axis Dysfunction: Hyperactivation vs Adrenal Fatigue06:28 – How Chronic Stress Damages the Gut08:14 – What Chronic Cortisol Does to the Immune System10:50 – The Self-Reinforcing Stress–Gut–Inflammation Loop11:40 – Identifying Your Dominant Pattern: Adrenal, Gut or Immune?14:38 – What Working With the Triangle Actually Looks Like (3 Core Priorities)20:40 – Why Addressing All Three Systems Creates Durable ResultsIf you’ve ever said, “I’ve tried everything,” this episode will help you see what’s been missing and what to do next.RESOURCES: Grab all the links and resources mentioned in this episode at https://www.nicolegoodehealth.com/the-goode-health-podcast/episode-116DISCLAIMER: The content in this podcast and related website is not intended to be a substitute for medical advice. It is not intended to be used to diagnose or treat, instead it is designed to help educate and inspire. Always seek the advice of a professional medical practitioner or qualified health practitioner. Never ignore or disregard advice given to you based on information in this podcast or related website and do not delay in seeking medical advice.

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