The AI riff (Ep25) - Diagnosis AI

What happens when Microsoft builds a superintelligence team—but doesn’t chase AGI? Instead, they point their smartest minds at one thing: helping doctors diagnose disease. In this episode, we riff on the strategy behind that decision—and why narrow, high-stakes AI might be the smartest kind.Kyle, Mario, and Rob unpack Microsoft’s approach to human-in-the-loop AI, the business model implications of medical breakthroughs, and what it means when AI becomes part of the healthcare supply chain. But things get personal, too: What happens when profit motives clash with cures? Can AI be a tool for humanity if it’s built by corporations?We also explore:* The slow pivot away from generalist AI toward specialist agents* Open-source cellular modeling and the open-access vs. monetized AI debate* The latest dev tools, including Cursor’s multi-step agent pipelineAnd yeah, we check in on Copilot, take a quick detour into Ask Jeeves nostalgia, and pitch a new hit show: Diagnosis: AI.A big episode on the future of medicine, money, and the role of humans in AI’s last mile.