The Art of Drug Synthesis

Provides detailed coverage of medicinal and synthetic chemistry's crucial role in drug discovery, including the tools and hurdles involved in the process. The core of the material focuses on the chemical syntheses and mechanisms of action for various classes of marketed drugs, such as HIV reverse transcriptase inhibitors, quinolone antibiotics, antidiabetics (PPAR agonists), antihypertensives (ACE inhibitors and AT1 antagonists), cholesterol absorption inhibitors, and treatments for depression and insomnia. Specific examples include the syntheses of Oseltamivir (Tamiflu), Levofloxacin, and Ezetimibe, illustrating both laboratory-scale development and considerations for industrial process scale-up. Overall, the text serves as a technical resource detailing the molecular complexity and manufacturing challenges associated with modern pharmaceutical compounds.You can listen and download our episodes for free on more than 10 different platforms:https://linktr.ee/pharmacy_simpleProduced by:https://www.podcaistudio.com/