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EPISODE · Apr 20, 2026 · 5 MIN

The ashwagandha sleep mechanism nobody talks about

from NutraSift: The nutraceutical innovation podcast · host Siftlink SA

Most of ashwagandha's sleep marketing is based on cortisol-lowering data. But the actual sleep compound may be triethylene glycol, a simple organic molecule found in the leaf (not the root) that shows direct sleep-inducing activity in animal models via GABA-A modulation. KSM-66 uses only root. The sleep mechanism may be in the part of the plant the most popular extract throws away.Publications of interest:https://pubmed.ncbi.nlm.nih.gov/28207892/, https://pmc.ncbi.nlm.nih.gov/articles/PMC5313221/, https://pmc.ncbi.nlm.nih.gov/articles/PMC10281725/

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